Neonatal resuscitation is a high acuity, low occurrence event. Limited high-quality evidence informs neonatal resuscitation treatment recommendations. Our group seeks to identify the best methods to monitor and perform neonatal resuscitation, with the ultimate goal of optimizing clinical outcomes for high-risk infants.
We defined SpO2 trajectories after birth and delivery room respiratory interventions for 200 infants with three distinct phenotypes of cyanotic congenital heart disease. These results inform delivery room management of these high-risk populations.
Journal of Perinatology
Transitional oxygen physiology for cyanotic congenital heart disease
In this multicenter cohort of infants receiving chest compressions following delivery, recognizable pre-birth risk factors as well as resuscitation interventions associated with increased and decreased odds of achieving return of spontaneous circulation (ROSC) were identified.
Delivery Room Cardiopulmonary Resuscitation
This is an updated ILCOR systematic review of 16 studies including 579 infants with ongoing CPR at 10 minutes after birth. These infants are at high risk for mortality and neurodisability, but survival without moderate or severe neuroimpairment is possible. One specified duration of CPR is unlikely to uniformly predict survival or survival without neuroimpairment.
Duration of Resuscitation at Birth
Dr. Foglia is an Assistant Professor of Pediatrics at the University of Pennsylvania Perelman School of Medicine and an academic neonatologist at the Children’s Hospital of Philadelphia and the Hospital of the University of Pennsylvania.
Dr. Foglia’s research aims to characterize the epidemiology of neonatal resuscitation, to improve monitoring and clinical performance during resuscitation, and to identify interventions to prevent mortality and long-term disability in high-risk infants.